Purine nucleotides
Selleck Chemical LLC BRM/BRG1 ATP Inhibitor-1
BRM/BRG1 ATP Inhibitor-1 (Compound 14) is an orally active inhibitors of Brahma Homolog (BRM)/SMARCA2 (BRG1) with IC50s below 0 005 M
Medchemexpress LLC Adenosine dialdehyde | 34240-05-6 | MFCD00056960 | 99.0% | 265.23 g/mol | C10H11N5O4 | 10MG
Adenosine dialdehyde is a purine nucleoside analogue that acts as a potent inhibitor of S-adenosylhomocysteine hydrolase (SAHH). It is used as a biochemical research reagent to investigate methylation pathways and methyltransferase activity, and is supplied in solid milligram quantities and as a 10 mM solution in DMSO for convenient assay preparation.
- Potent SAHH inhibitor for methylation pathway studies.
- Supplied in both solid and ready-to-use solution formats.
- High stated purity for analytical and research applications.
- Compatible with enzyme inhibition assays and cellular studies.
- Provided with datasheet, certificate of analysis, and safety data sheet for compliance.
Sigma Aldrich Fine Chemicals Biosciences Coenzyme A Trilithium Salt | ≥85% Purity | Mol Wt: 767.5 | ®93-18-4-3 | 10 mg
Coenzyme A trilithium salt | Purity: ≥85% | Mol Wt: 767.5 | CAS No: 93-18-4-3 | Biochemical cofactor involved in metabolic pathways and energy production via acyl transfer and thioesterification | 10mg
Apexbio Technology LLC LDE225 Diphosphate 1218778-77-8 5mg
LDE225 Diphosphate (CAS 1218778-77-8) is a highly potent and selective antagonist of the Smoothened (Smo) receptor a seven-transmembrane protein involved in the Hedgehog (Hh) signaling pathway LDE225 inhibits Smo with IC50 values of 1 3 nM for murine and 2 5 nM for human Smo resulting in suppression of Hh signaling This pathway is implicated in cellular differentiation proliferation and oncogenesis In vitro LDE225 selectively binds Smo inhibiting Hh-dependent tumor cell growth In vivo it demonstrates dose-dependent antitumor efficacy in medulloblastoma xenograft mouse models LDE225 continues to be explored as a research tool and therapeutic candidate in Hh pathway-driven malignancies
![Medchemexpress LLC 1-[3-(difluoromethyl)-1,2-thiazol-5-yl]-3-[2-fluoro-5-(hydroxymethyl)-4-pyridinyl]urea | 2270879-17-7 | 98.9% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000231785.png-250.jpg)
Medchemexpress LLC 1-[3-(difluoromethyl)-1,2-thiazol-5-yl]-3-[2-fluoro-5-(hydroxymethyl)-4-pyridinyl]urea | 2270879-17-7 | 98.9% | 50 MG
BRM/BRG1 ATP Inhibitor-1 is a potent, allosteric small-molecule inhibitor of the BRM (SMARCA2) and BRG1 (SMARCA4) ATPase activities used in epigenetic and cancer research.
- Potent allosteric dual inhibitor of BRM and BRG1 ATPase activities (reported IC50 < 5 nM).
- Molecular formula C11H9F3N4O2S; molecular weight 318.27 g/mol.
- Typical purity ≥98% (example batch purity 98.86%), supplied as a solid powder.
- Soluble in DMSO; suitable for cell-based and biochemical assays probing SMARCA2/4 function.
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5′-triphosphate disodium salt solution Crystalline ATP, HPLC purified, aqueous solution for RNA transcription | 987-65-5 | MFCD00080339 | 25umo
Adenosine 5′-triphosphate disodium salt solution Crystalline ATP, HPLC purified, aqueous solution for RNA transcription | 987-65-5 | MFCD00080339 | 25umo
Medchemexpress LLC ATP-polyamine-biotin | 1800401-93-7 | MFCD29924712 | >98.0% | 945.85 g/mol | C32H58N11O14P3S | 10 MG
ATP-polyamine-biotin is a cell-permeable ATP analogue used as an efficient kinase co-substrate to transfer a biotin tag to kinase substrates in vitro and in live cells. It facilitates detection and enrichment of phosphorylated proteins for downstream analysis in biochemical and cell-based assays.
- Promotes biotin labeling of kinase substrates in live cells.
- Functions as an efficient ATP cosubstrate for kinases.
- Enables detection and enrichment of phosphorylated proteins.
- Provided with high purity suitable for biochemical assays.
- Available in multiple pack sizes, including 10 mg.
Medchemexpress LLC Adenosine-13C5 | 159496-13-6 | 99.9% | 272.20 | C10H13N5O4 (five 13C atoms) | 10 MG
Adenosine-13C5 is a stable isotope-labeled adenosine supplied as a powdered research reagent for use as an internal standard or tracer in mass spectrometry and metabolic studies. It contains five 13C-labeled carbons, has a molecular weight of 272.20, and is typically supplied with high purity for quantitative analysis.
- Stable isotope-labeled internal standard for quantitative LC-MS/MS.
- Five 13C labels produce a clear mass shift for tracer studies.
- High purity (99.9%) supports accurate quantitation.
- Supplied as a powder suitable for long-term storage under frozen conditions.
- Available in small mg-scale quantities for analytical applications.